Local-first health intelligence
Ask your DNA anything. Privately.
Bring the 23andMe, MyHeritage or AncestryDNA file you already have. Get honest, cited answers about your genes, your metabolism, and the supplements and peptides everyone’s talking about — then let Indaga tune your day. Nothing ever leaves your machine.
Bring the file you already have
- 23andMeraw data (.txt / .zip)
- MyHeritageraw DNA export
- AncestryDNAraw DNA export
- VCF / gVCFsequencing output
- Sleep window
- Biological Midnight
- Eating window
- Light window
Find your Biological Midnight.
A 24-hour dial of your own circadian phase, so you can time light, food and sleep to your biology — not a generic schedule.
The problem
You have more health data than ever — and no idea what it means for how you feel today.
Five silos, zero synthesis.
Your DNA is in one app, sleep in another, glucose in a third. Nothing reads them together — so you never see the why.
Reports are static; life is daily.
A one-time DNA report tells you a fact about your 80-year-old self, then collects dust. It won’t help you time tonight’s dinner.
The affordable tools are shallow.
Black-box apps overstate your risk with false precision, and cite nothing you can check.
And your data isn’t yours.
Upload it, and — as 23andMe showed — it can become an asset to be sold to the highest bidder.
There was no daily, rigorous engine that uses your deep history to optimize your current day while keeping your data under your control. So we built one.
What you can ask
The questions the experts argue about — answered from your own DNA.
Caffeine, methylation, medication response, the latest peptide. Ask in plain language; get a calibrated, cited answer — and an honest note on what your data could and couldn’t see.
“Am I a slow caffeine metabolizer?”
Slow CYP1A2 keeps caffeine active hours longer — and changes when you should stop.
CYP1A2 · ADORA2AMetabolism“Do I have an MTHFR variant — should I take methylfolate?”
We show your genotype and what the evidence actually supports — not a supplement pitch.
MTHFR · COMT · VDRSupplements & peptides“What's my COMT status — warrior or worrier?”
How you clear dopamine under stress, with the honest size of the effect.
COMT Val158MetTraits & carrier“How do I metabolize this medication?”
Pharmacogenomics with calibrated guidance — and an honest note on what your chip could see.
CYP2D6 · CYP2C19 · CPICMedication
Your data stays yours
The original mistake was uploading it.
When 23andMe filed for bankruptcy, the genetic data of 15 million people became an asset in a $305M sale — and privacy regulators told customers to delete their accounts. Your genome identifies your relatives and can never be changed after a leak. It should never sit on a company’s balance sheet.
Indaga is built local-first. Your raw DNA and health data live only on your own machine; the reference databases come to your data, not the other way around. There is no database of you to lose, leak, or sell.
Nothing is uploaded
Raw files and indexes stay in a local, permission-gated folder on your device.
No per-variant egress
Annotations run from databases downloaded to your machine — your genes aren’t queried in the cloud.
Ships zero personal data
The engine is open and inspectable; your data is never part of it.
Coverage
Screened against the same panels clinicians use.
Industry-standard, graded, citable gene panels — and an honest account of what a consumer chip can and cannot see.
- 84 genes
Actionable secondary findings
The medically-actionable, return-of-results genes recommended for reporting.
ACMG SF v3.3 (PMID 40568962)
- 113 genes
Carrier screening
The standard pan-ethnic carrier panel — 97 autosomal-recessive + 16 X-linked.
ACMG 2021 (PMID 34285390)
- 6,000+ relationships
Gene–disease validity
Every gene–disease link graded Definitive → Strong → Moderate → Limited → Disputed → Refuted.
GenCC + ClinGen
- PanelApp
Diagnostic panels
Curated green-gene diagnostic panels for focused questions.
Genomics England
- PGS Catalog
Polygenic scores
Published polygenic scores applied to your data, with overlap QC and percentiles.
PGS Catalog
- CPIC / DPWG
Pharmacogenomics
Drug-gene diplotypes and dosing guidance, gated on what was actually callable.
PharmCAT 3.2.0
Annotation sources — all public, peer-reviewed, queried locally
Proof
Not a concept. A working system, with results.
Indaga’s engine has been run end-to-end on real people — joining DNA, blood, wearable and glucose into one model, and refuting findings that didn’t hold up.
- 4
- people taken all the way through, with full results
- 8
- false-positive “pathogenic” findings refuted in one consumer report
- 3×
- independent cross-validations before a finding reaches you
- 1
- engine joining DNA, blood, wearable and glucose — not five silos
Where Indaga sits
High-rigor and accessible — the corner no one else occupies.
Consumer reports are shallow. Longevity clinics are gatekept. Single-axis apps read one stream. Indaga is multi-omic, cited, daily — and yours.
| Indaga | Consumer DNA reports | Longevity / blood | Single-axis apps | |
|---|---|---|---|---|
| Uses the DNA file you already have | Yes | Partial | No | No |
| Data never leaves your machine | Yes | No | No | No |
| Multi-omic (DNA × glucose × sleep × labs) | Yes | No | Partial | No |
| Daily circadian + metabolic engine | Yes | No | No | Partial |
| Every claim cited to a public source | Yes | No | Partial | No |
| Honest about what wasn’t measured | Yes | No | No | No |
| Free to start (no new test to buy) | Yes | Partial | No | No |
Your data stays yours
Raw DNA and health data live only on your machine. Nothing is uploaded — there is no database of you to leak, sell, or lose.
It shows its work
Every claim traces to a named, public, peer-reviewed source and to a record in your own Healthlake. If you want to check us, you can.
It’s honest about uncertainty
Absence is never “normal.” A test you never took returns “not measured,” not “you’re fine.” We’d rather drop a finding than alarm you with a false one.
Every claim traces back to a named public source — and to a record in your own Healthlake. See the method →
Be first in line.
Indaga is in active development. Join the waitlist for early access and occasional, substance-only updates.